FCGR1A

Fc fragment of IgG receptor Ia
المعرفات
الأسماء المستعارة	high affinity immunoglobulin gamma Fc receptor I, Fc-gamma receptor I A1, FcRI, FCGR1A, Fc gamma receptor Ia, IgG Fc receptor I, Fc-gamma RI, fcgammaRIa, fc-gamma RIA, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64)
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

FCGR1A‏ (Fc fragment of IgG receptor Ia) هوَ بروتين يُشَفر بواسطة جين FCGR1A في الإنسان.^[1]^[2]^[3]

الوظيفةعدل

الأهمية السريريةعدل

المراجععدل

^ "The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21". Cytogenetics and Cell Genetics. 73 (3): 157–63. سبتمبر 1996. doi:10.1159/000134330. PMID 8697799.
^ "Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1". Cytogenetics and Cell Genetics. 82 (1–2): 71–4. نوفمبر 1998. doi:10.1159/000015067. PMID 9763663.
^ "Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقةعدل

"IgA Fc receptors". Annual Review of Immunology. 21: 177–204. 2003. doi:10.1146/annurev.immunol.21.120601.141011. PMID 12524384.
"Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products". The Journal of Biological Chemistry. 267 (22): 15692–700. أغسطس 1992. PMID 1379234.
"Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure". The Journal of Experimental Medicine. 176 (4): 1115–23. أكتوبر 1992. doi:10.1084/jem.176.4.1115. PMC 2119393. PMID 1402657.
"Novel Fc gamma receptor I family gene products in human mononuclear cells". The Journal of Clinical Investigation. 90 (5): 2102–9. نوفمبر 1992. doi:10.1172/JCI116094. PMC 443278. PMID 1430234.
"Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene". The Journal of Biological Chemistry. 266 (20): 13449–55. يوليو 1991. PMID 1830050.
"Induction of Fc (IgG) receptor(s) by simian cytomegaloviruses in human embryonic lung fibroblasts". Intervirology. 29 (6): 339–45. 1989. doi:10.1159/000150065. PMID 2852656.
"Isolation and expression of functional high-affinity Fc receptor complementary DNAs". Science. 243 (4889): 378–81. يناير 1989. doi:10.1126/science.2911749. PMID 2911749.
"Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI)". Nucleic Acids Research. 16 (24): 11824. ديسمبر 1988. doi:10.1093/nar/16.24.11824. PMC 339124. PMID 2974947.
"The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI". Experimental Hematology. 22 (7): 599–606. يوليو 1994. PMID 7516890.
"Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy". Blood. 82 (3): 931–9. أغسطس 1993. PMID 7687898.
"Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn". The Journal of Experimental Medicine. 180 (3): 1165–70. سبتمبر 1994. doi:10.1084/jem.180.3.1165. PMC 2191633. PMID 8064233.
"Human high-affinity Fc gamma RI (CD64) gene mapped to chromosome 1q21.2-q21.3 by fluorescence in situ hybridization". Human Genetics. 93 (1): 13–5. يناير 1994. doi:10.1007/BF00218905. PMID 8270248.
"Functional association between the human myeloid immunoglobulin A Fc receptor (CD89) and FcR gamma chain. Molecular basis for CD89/FcR gamma chain association". The Journal of Biological Chemistry. 270 (50): 29781–7. ديسمبر 1995. doi:10.1074/jbc.270.50.29781. PMID 8530370.
"Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines". Blood. 91 (6): 2108–17. مارس 1998. PMID 9490697.
"Differential interaction of Crkl with Cbl or C3G, Hef-1, and gamma subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (Fc gamma RI)". Journal of Immunology. 161 (10): 5555–63. نوفمبر 1998. PMID 9820532.
"The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes". European Journal of Immunology. 28 (11): 3423–34. نوفمبر 1998. doi:10.1002/(SICI)1521-4141(199811)28:11<3423::AID-IMMU3423>3.0.CO;2-2. PMID 9842885.
"Histidine-rich glycoprotein regulates the binding of monomeric IgG and immune complexes to monocytes". International Immunology. 11 (8): 1275–82. أغسطس 1999. doi:10.1093/intimm/11.8.1275. PMID 10421785.
"The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells". The Journal of Biological Chemistry. 275 (27): 20480–7. يوليو 2000. doi:10.1074/jbc.M909462199. PMID 10781611.

هذه بذرة مقالة عن جين على كروموسوم 1 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid8697799-1] "The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21". Cytogenetics and Cell Genetics. 73 (3): 157–63. سبتمبر 1996. doi:10.1159/000134330. PMID 8697799.

[pmid9763663-2] "Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1". Cytogenetics and Cell Genetics. 82 (1–2): 71–4. نوفمبر 1998. doi:10.1159/000015067. PMID 9763663.

[entrez-3] "Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)". مؤرشف من الأصل في 2010-12-05.

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[2]

[3]