جينداتا (بيانات الجينات)

معلومات عامة
البلد	سويسرا
التأسيس	1997
النوع	خاصة
المقر الرئيسي	بازل ، سويسرا
موقع الويب	genedata.com
المنتجات	انظر إلى القائمة المفصلة
أهم الشخصيات	اوثمر فانز (كبير الإداريين التنفيذيين)
الموظفون	120+

جينداتا هي موفر لحلول معلوماتية حيوية ومقرها مدينة بازل في سويسرا. وتقوم بتوفير المنتجات لصناعة الدواء والتقنية الحيوية والزراعة والأكاديميا لجميع أنحاء العالم. وقد تلقت جينداتا اهتمام ايجابي كبير في عدة منشورات صناعية مستقلة على سبيل المثال الجينوم ويب (GenomeWeb)، والبايو انفورم (BioInform)، وكذلك بايو أي تي وورلد (Bio-IT World).

وتقوم جينداتا كعضو في اتحاد انوميد بريدتوكس InnoMed PreTox ^{[الإنجليزية]} للأبحاث بالتعاون مع شركات الأدوية الأوروبية على استعمال علم الوراثة السُمي في عمليات التنمية الصيدلانية.

المنتجات عدل

فيلسفور الجينداتا - يتمحور الهدف فيه حول إدارة المعلومات البحثية
فرز أو فحص الجينداتا - مشروع حل الإنتاجية الفائقة ^[2]^[3] والفحص عالي المحتوى^[4] لإدارة البيانات وتحليلها
الجينداتا التعبيري - منصة اكتشاف البيوماركر والتي تقوم بدمج وتحليل التعبير الجيني^[5]

,^[6]^[7]^[8]^[9]^[10]^[11]^[12]^[13]^[14]^[15]^[16]^[17]^[18]^[19] البروتيوميات,^[20]^[21] والايض, فضلاً عن مشاريع تمتد عبر مجالات التكنولوجيا المختلفة كما في علم الوراثة السمي^[22]

وصلات خارجية عدل

موقع الجينداتا الرسمي

انظر أيضاً عدل

المراجع عدل

^ مُعرِّف قاعدة بيانات البحث العالمية (GRID): grid.424959.7.
^ Liming Chang Milbauer, Peng Wei, Judy Enenstein, Aixiang Jiang, Cheryl A. Hillery, J. Paul Scott, Stephen C. Nelson, Vidya Bodempudi, James N. Topper, Ruey-Bing Yang, Betsy Hirsch, Wei Pan, and Robert P. Hebbel, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings Genetic endothelial systems biology of sickle stroke risk", Blood. 2008; 111:3872-3879
^ Zhijin Wu, Dongmei Liu, and Yunxia Sui, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate ", J Biomol Screen. 2008; 13:159-167
^ Duerr et al. "Robust hit identification by quality assurance and multivariate data analysis of a high-content, cell-based assay", J Biomol Screen. 2007 Dec;12(8):1042-9 [1] نسخة محفوظة 02 يونيو 2010 على موقع واي باك مشين.
^ Nadine Zidek, Juergen Hellmann, Peter-Juergen Kramer, and Philip G. Hewitt, "Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays", Toxicol. Sci. 2007; 99(1): p. 289-302
^ Walter Lucchesi, Gareth Brady, Oliver Dittrich-Breiholz, Michael Kracht, Rainer Russ, and Paul J. Farrell, "Differential gene regulation by Epstein-Barr virus Type 1 and Type 2 EBNA2",J Virol. 2008 May 14
^ Ramiro Dip, Sarah Lenz, Jean-Philippe Antignac, Bruno Le Bizec, Hans Gmuender, and Hanspeter Naegeli, "Global gene expression profiles induced by phytoestrogens in human breast cancer cells",Endocr. Relat. Cancer. 2008; 15:161-173
^ Andrea J. O'Hara, Wolfgang Vahrson, and Dirk P. Dittmer, "Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma",Blood. 2008; 111:2347-2353
^ Benita K.T. Tan, Lay Keng Tan, Kun Yu, Puay Hoon Tan, Ming Lee, Lang Hiong Sii, Chow Yin Wong, Gay Hui Ho, Allen W.Y. Yeo, Pierce K.H. Chow, Heng Nung Koong, Wei Sean Yong, Dennis T.H. Lim, London L.P.J. Ooi, Khee Chee Soo, and Patrick Tan, "Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer",Clin. Cancer Res. 2008; 14:461-469
^ Suk Mei Wang, London Lucien P.J. Ooi, and Kam M. Hui, "Identification and Validation of a Novel Gene Signature Associated with the Recurrence of Human Hepatocellular Carcinoma", Clin. Cancer Res., Nov 2007; 13: 6275 - 6283
^ Siew Leng Tai, Pascale Daran-Lapujade, Michael C. Walsh, Jack T. Pronk, and Jean-Marc Daran, "Acclimation of Saccharomyces cerevisiae to Low Temperature: A Chemostat-based Transcriptome Analysis", Mol. Biol. Cell, Oct 2007; 10.1091/mbc.E07-02-0131
^ Carsten Lange, Diane Starrett, Julia Goetsch, Volker Gerke, and Ursula Rescher, "Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25", J. Leukoc. Biol. published 12 September 2007, 10.1189/jlb.0307158
^ Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Jul 2007; 77: 165 - 171
^ Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, and Brian G. Van Ness, "A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma", Cancer Res., May 2007; 67: 4069 - 4078
^ Kerstin Stemmer, Heidrun Ellinger-Ziegelbauer, Hans-Juergen Ahr, and Daniel R. Dietrich, "Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis", Cancer Res., May 2007; 67: 4052 - 4068
^ Jeffrey D. Lande, Jagadish Patil, Na Li, Todd R. Berryman, Richard A. King, and Marshall I. Hertz, "Novel Insights into Lung Transplant Rejection by Microarray Analysis", Proceedings of the ATS, Jan 2007; 4: 44 - 51
^ Thorsten Müller, Caoimhin G. Concannon, Manus W. Ward, Ciara M. Walsh, Anca L. Tirniceriu, Florian Tribl, Donat Kögel, Jochen H.M. Prehn, and Rupert Egensperger, "Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD)", Mol. Biol. Cell, Jan 2007; 18: 201 - 210
^ Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Mar 2007; 10.1095/biolreprod.106.059493
^ Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler, "The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1alpha", J. Immunol., Mar 2007; 178: 3198 - 3207
^ Sebastian Wiese, Thomas Gronemeyer, Rob Ofman, Markus Kunze, Claudia P. Grou, Jose A. Almeida, Martin Eisenacher, Christian Stephan, Heiko Hayen, Lukas Schollenberger, Thomas Korosec, Hans R. Waterham, Wolfgang Schliebs, Ralf Erdmann, Johannes Berger, Helmut E. Meyer, Wilhelm Just, Jorge E. Azevedo, Ronald J. A. Wanders, and Bettina Warscheid, "Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling", Mol. Cell. Proteomics. published 2 September 2007, 10.1074/mcp.M700169-MCP200
^ Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, and Setsuo Hirohashi, "Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma", Mol. Cell. Clin. Cancer Res., Feb 2007; 13: 799 - 805
^ Heidrun Ellinger-Ziegelbauer, Hans Gmuender, Arnd Brandenburg, Hans Juergen Ahr, "Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies", Mutation Research 637 2007 23-39

[b73d8dc308c4d4d2bc1358b6a408df62d4ece852-1] مُعرِّف قاعدة بيانات البحث العالمية (GRID): grid.424959.7.

[2] Liming Chang Milbauer, Peng Wei, Judy Enenstein, Aixiang Jiang, Cheryl A. Hillery, J. Paul Scott, Stephen C. Nelson, Vidya Bodempudi, James N. Topper, Ruey-Bing Yang, Betsy Hirsch, Wei Pan, and Robert P. Hebbel, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate High-Throughput Screenings Genetic endothelial systems biology of sickle stroke risk", Blood. 2008; 111:3872-3879

[3] Zhijin Wu, Dongmei Liu, and Yunxia Sui, "Quantitative Assessment of Hit Detection and Confirmation in Single and Duplicate ", J Biomol Screen. 2008; 13:159-167

[4] Duerr et al. "Robust hit identification by quality assurance and multivariate data analysis of a high-content, cell-based assay", J Biomol Screen. 2007 Dec;12(8):1042-9 [1] نسخة محفوظة 02 يونيو 2010 على موقع واي باك مشين.

[5] Nadine Zidek, Juergen Hellmann, Peter-Juergen Kramer, and Philip G. Hewitt, "Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays", Toxicol. Sci. 2007; 99(1): p. 289-302

[6] Walter Lucchesi, Gareth Brady, Oliver Dittrich-Breiholz, Michael Kracht, Rainer Russ, and Paul J. Farrell, "Differential gene regulation by Epstein-Barr virus Type 1 and Type 2 EBNA2",J Virol. 2008 May 14

[7] Ramiro Dip, Sarah Lenz, Jean-Philippe Antignac, Bruno Le Bizec, Hans Gmuender, and Hanspeter Naegeli, "Global gene expression profiles induced by phytoestrogens in human breast cancer cells",Endocr. Relat. Cancer. 2008; 15:161-173

[8] Andrea J. O'Hara, Wolfgang Vahrson, and Dirk P. Dittmer, "Gene alteration and precursor and mature microRNA transcription changes contribute to the miRNA signature of primary effusion lymphoma",Blood. 2008; 111:2347-2353

[9] Benita K.T. Tan, Lay Keng Tan, Kun Yu, Puay Hoon Tan, Ming Lee, Lang Hiong Sii, Chow Yin Wong, Gay Hui Ho, Allen W.Y. Yeo, Pierce K.H. Chow, Heng Nung Koong, Wei Sean Yong, Dennis T.H. Lim, London L.P.J. Ooi, Khee Chee Soo, and Patrick Tan, "Clinical Validation of a Customized Multiple Signature Microarray for Breast Cancer",Clin. Cancer Res. 2008; 14:461-469

[10] Suk Mei Wang, London Lucien P.J. Ooi, and Kam M. Hui, "Identification and Validation of a Novel Gene Signature Associated with the Recurrence of Human Hepatocellular Carcinoma", Clin. Cancer Res., Nov 2007; 13: 6275 - 6283

[11] Siew Leng Tai, Pascale Daran-Lapujade, Michael C. Walsh, Jack T. Pronk, and Jean-Marc Daran, "Acclimation of Saccharomyces cerevisiae to Low Temperature: A Chemostat-based Transcriptome Analysis", Mol. Biol. Cell, Oct 2007; 10.1091/mbc.E07-02-0131

[12] Carsten Lange, Diane Starrett, Julia Goetsch, Volker Gerke, and Ursula Rescher, "Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25", J. Leukoc. Biol. published 12 September 2007, 10.1189/jlb.0307158

[13] Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Jul 2007; 77: 165 - 171

[14] Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, and Brian G. Van Ness, "A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma", Cancer Res., May 2007; 67: 4069 - 4078

[15] Kerstin Stemmer, Heidrun Ellinger-Ziegelbauer, Hans-Juergen Ahr, and Daniel R. Dietrich, "Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis", Cancer Res., May 2007; 67: 4052 - 4068

[16] Jeffrey D. Lande, Jagadish Patil, Na Li, Todd R. Berryman, Richard A. King, and Marshall I. Hertz, "Novel Insights into Lung Transplant Rejection by Microarray Analysis", Proceedings of the ATS, Jan 2007; 4: 44 - 51

[17] Thorsten Müller, Caoimhin G. Concannon, Manus W. Ward, Ciara M. Walsh, Anca L. Tirniceriu, Florian Tribl, Donat Kögel, Jochen H.M. Prehn, and Rupert Egensperger, "Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD)", Mol. Biol. Cell, Jan 2007; 18: 201 - 210

[18] Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky, "Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation", Biol Reprod, Mar 2007; 10.1095/biolreprod.106.059493

[19] Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler, "The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1alpha", J. Immunol., Mar 2007; 178: 3198 - 3207

[20] Sebastian Wiese, Thomas Gronemeyer, Rob Ofman, Markus Kunze, Claudia P. Grou, Jose A. Almeida, Martin Eisenacher, Christian Stephan, Heiko Hayen, Lukas Schollenberger, Thomas Korosec, Hans R. Waterham, Wolfgang Schliebs, Ralf Erdmann, Johannes Berger, Helmut E. Meyer, Wilhelm Just, Jorge E. Azevedo, Ronald J. A. Wanders, and Bettina Warscheid, "Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling", Mol. Cell. Proteomics. published 2 September 2007, 10.1074/mcp.M700169-MCP200

[21] Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, and Setsuo Hirohashi, "Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma", Mol. Cell. Clin. Cancer Res., Feb 2007; 13: 799 - 805

[22] Heidrun Ellinger-Ziegelbauer, Hans Gmuender, Arnd Brandenburg, Hans Juergen Ahr, "Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies", Mutation Research 637 2007 23-39

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البلد	سويسرا^[1]
التأسيس	1997
النوع	خاصة
المقر الرئيسي	بازل ، سويسرا
موقع الويب	genedata.com