بروجستيرون: الفرق بين النسختين
| [نسخة منشورة] | [نسخة منشورة] |
تم حذف المحتوى تمت إضافة المحتوى
ط بوت:إضافة قالب تصفح {{وسائل تحديد النسل الهرمونية}}+ترتيب (8.6); تغييرات تجميلية |
Mahmoudalrawi (نقاش | مساهمات) لا ملخص تعديل |
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سطر 13:
| MedlinePlus = a604017
| pregnancy_category = B ([[United States|USA]])
| routes_of_administration =
<!--Pharmacokinetic data-->
| bioavailability = 10–15٪ (فموي)<ref name="ArunNarendra2012">{{cite book|author1=Nagrath Arun|author2=Malhotra Narendra|author3=Seth Shikha|title=Progress in Obstetrics and Gynecology--3|url=https://books.google.com/books?id=AS3UBAAAQBAJ&pg=PA370|date=15 December 2012|publisher=Jaypee Brothers Medical Publishers Pvt. Ltd.|isbn=978-93-5090-575-3|pages=370–}}</ref>
| protein_bound = 96%–99%
| metabolism = [[كبد]] ([[CYP2C19]], [[سيتوكروم 3A4]], [[CYP2C9]])<ref name="pmid9328296">{{cite journal | vauthors = Yamazaki H, Shimada T | title = Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes | journal = Archives of Biochemistry and Biophysics | volume = 346 | issue = 1 | pages = 161–9 | date = October 1997 | pmid = 9328296 | doi = 10.1006/abbi.1997.0302 }}</ref><ref name="McKayWalters2013">{{cite book | author1 = Gerard A. McKay | author2 = Matthew R. Walters | title = Lecture Notes: Clinical Pharmacology and Therapeutics | url = https://books.google.com/books?id=OGOqcfN_Cc8C&pg=PT33 | date = 6 February 2013 | publisher = John Wiley & Sons | isbn = 978-1-118-34489-7 | page = 33}}</ref>
| elimination_half-life = 16–18 ساعة (فموي)<ref name="Zutshi2005">{{cite book | author = Zutshi | title = Hormones in Obstetrics and Gynaecology | url = https://books.google.com/books?id=IBxBbaDjXw0C&pg=PA74 | date = 1 January 2005 | publisher = Jaypee Brothers Publishers | isbn = 978-81-8061-427-9 | page = 74}}</ref>
| excretion = [[كلية (عضو)|كلية]]
<!--Identifiers-->
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