سيتوكين: الفرق بين النسختين
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تم حذف المحتوى تمت إضافة المحتوى
سطر 42:
ومستقبلات الكيموكين 7TMHR وغيرها.
==الاستخدام الطبي كدواء==
Some cytokines have been developed into [[Biologic medical product|protein therapeutics]] using [[recombinant DNA]] technology.<ref>Horst Ibelgaufts. [http://www.copewithcytokines.de/cope.cgi?key=recombinant%20cytokines Recombinant cytokines] in Cytokines & Cells Online Pathfinder Encyclopedia Version 31.4 (Spring/Summer 2013 Edition)</ref> Recombinant cytokines being used as drugs as of 2014 include:<ref>Dimiter S. Dimitrov. [http://link.springer.com/protocol/10.1007/978-1-61779-921-1_1 Therapeutic Proteins].Chapter 1 in Therapeutic Proteins: Methods and Protocols, Editors: Vladimir Voynov, Justin A. Caravella. Volume 899 of Methods in Molecular Biology. Springer Science+Business Media, LLC 2012. ISBN 978-1-61779-920-4 (Print) 978-1-61779-921-1 (Online)</ref>
* [[Bone morphogenetic protein]] (BMP), used to treat bone-related conditions
* [[Erythropoietin]] (EPO), used to treat [[anemia]]
* [[Granulocyte colony-stimulating factor]] (G-CSF), used to treat [[neutropenia]] in cancer patients
* [[Granulocyte macrophage colony-stimulating factor]] (GM-CSF), used to treat [[neutropenia]] and [[fungal infections]] in cancer patients
* [[Interferon alfa]], used to treat [[hepatitis C]] and [[multiple scelerosis]]
* [[Interferon beta]], used to treat [[multiple scelerosis]]
* [[Interleukin 2]] (IL-2), used to treat cancer.
* [[Interleukin 11]] (IL-11), used to treat [[thrombocytopenia]] in cancer patients.
* [[Interferon gamma]] is used to treat [[chronic granulomatous disease]]<ref>{{cite journal|last1=Woodman|first1=RC|last2=Erickson|first2=RW|last3=Rae|first3=J|last4=Jaffe|first4=HS|last5=Curnutte|first5=JT|title=Prolonged recombinant interferon-gamma therapy in chronic granulomatous disease: evidence against enhanced neutrophil oxidase activity.|journal=Blood|date=Mar 15, 1992|volume=79|issue=6|pages=1558–62|pmid=1312372}}</ref> and [[osteopetrosis]]<ref>{{cite journal|last1=Key LL|first1=Jr|last2=Rodriguiz|first2=RM|last3=Willi|first3=SM|last4=Wright|first4=NM|last5=Hatcher|first5=HC|last6=Eyre|first6=DR|last7=Cure|first7=JK|last8=Griffin|first8=PP|last9=Ries|first9=WL|title=Long-term treatment of osteopetrosis with recombinant human interferon gamma|journal=The New England Journal of Medicine|date=Jun 15, 1995|volume=332|issue=24|pages=1594–9|pmid=7753137|doi=10.1056/NEJM199506153322402}}</ref>
==انظر أيضا==
* [[أديبوكين]] Adipokine
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